I know the feeling. The only reason I keep an XP partition on my box is because I have clients call me asking questions that pertain to XP. Win is such a pain to keep running. Update your virus sigs, update your Adaware and Spybot sigs, run Win update to get the latest security patch, run virus scans, run mal-ware scans, pray that all this is enough.
I've half a mind to blow my XP partition away too! :P